Anovulation after Precocious Pubarche: Early Markers and Time Course in Adolescence1
نویسندگان
چکیده
منابع مشابه
Precocious pubarche in Thai children.
OBJECTIVE To describe the etiologies, clinical characteristics, and laboratory investigations of young Thai children being evaluated for precocious pubarche. MATERIAL AND METHOD The medical records of 41 children referred for evaluation of precocious presence of pubic hair at Songklanagarind Hospital between 1995 and 2011 were retrospectively reviewed. RESULTS The etiologies of precocious p...
متن کاملPolycystic ovaries after precocious pubarche: relation to prenatal growth.
BACKGROUND In 1998, we revealed a sequence departing from prenatal growth restraint in girls and evolving, through precocious pubarche (PP) in mid-childhood, towards anovulatory and hyperinsulinaemic hyperandrogenism. The latter condition fulfilled the criteria for the diagnosis of polycystic ovary syndrome (PCOS), which was then defined independently of the presence of polycystic ovaries (PCOs...
متن کاملEarly metformin therapy to delay menarche and augment height in girls with precocious pubarche.
OBJECTIVE To study the effects of early metformin treatment on menarche, height, and polycystic ovary syndrome (PCOS) markers. Low-birthweight (LBW) girls with precocious pubarche (PP) are at risk for an early menarche (<12 years), an adult stature below target level, and PCOS. Hyperinsulinemic insulin resistance is thought to be a key factor. DESIGN Open-label, randomized study. SETTING Un...
متن کاملPremature Pubarche before One Year of Age: Distinguishing between Mini-Puberty Variants and Precocious Puberty
BACKGROUND The aim of this study was to facilitate the distinction between the benign "mini-puberty of early infancy" and precocious puberty (PP). MATERIAL AND METHODS We compared 59 patients (21 boys and 38 girls) seen for pubic hair development before one year of age diagnosed as mini-puberty to 13 patients (2 boys) in whom pubertal development before one year revealed a PP. RESULTS The b...
متن کاملPrecocious pubarche is associated with SGA, prematurity, weight gain, and obesity.
BACKGROUND Perinatal stress is thought to underlie the Barker sequelae of low birth weight, of which precocious pubarche may be a manifestation. AIMS To explore whether prematurity as well as smallness for gestational age (SGA) predisposes to precocious pubarche, and the potential role of excess weight gain during childhood. METHODS Retrospective chart review of 89 children (79 girls) with ...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1999
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.84.8.5883